TY - JOUR T1 - The needs and medication experience of patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors: A systematic review JO - Farmacia Hospitalaria T2 - AU - Cachafeiro Pin,Ana Isabel AU - Villaverde Piñeiro,Laura AU - Martín Clavo,Susana AU - Silva Castro,Martha Milena SN - 11306343 M3 - 10.1016/j.farma.2023.02.002 DO - 10.1016/j.farma.2023.02.002 UR - https://www.revistafarmaciahospitalaria.es/es-translated-article-the-needs-medication-articulo-S1130634323000156 AB - ObjectiveSeveral studies quantitatively described patients with Chronic Myeloid Leukemia on active treatment with tyrosine kinase inhibitors, however there are few qualitative studies that focus their results on how to accompany patients in the course of the disease over time. The objective of this review is to find out what are the expectations, information needs and experiences that determine adherence to treatment with tyrosine kinase inhibitors in patients with Chronic Myeloid Leukemia in qualitative research articles published in the scientific literature. MethodsA systematic review of qualitative research articles published between 2003–2021 was carried out in PubMed/Medline, Web of Science and Embase databases. Main keywords used were: “Leukemia, Myeloid” and “Qualitative Research”. Articles on the acute phase or blast phase were excluded. Results184 publications were located. After elimination of duplicates, 6 (3%) were included and 176 (97%) publications were excluded. Studies show that the illness is a turning point in patients' lives, and they develop their own strategies for managing the adverse effects. The factors that determine medication experiences with tyrosine kinase inhibitors should be addressed by implementing personalized strategies: this would result in early detection of problems, reinforce education at each stage and promote open discussion about complex causes underlying the treatment failure. ConclusionsThis systematic review provides evidence that implementation personalized strategies must be done to address the factors that determine the illness experience with Chronic Myeloid Leukemia and receiving treatment with tyrosine kinase inhibitors. ER -